Ultrastructural localization of bcl-2 protein.
نویسندگان
چکیده
منابع مشابه
Ultrastructural Study of Rotavirus Replication and Localization of the Intermediate Capsid Protein VP6
Rotavirus, a triple-layered non-enveloped member of the Reoviridae family, obtained a transient membrane envelope when newly synthesized subviral particles bud into the endoplasmic reticulum (ER). As rotavirus particles mature, they lose their transient membrane and obtain outer layer. It is mostly believed that only double layered particles bud into the ER. The present study describes that the...
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BHRF1 is an Epstein-Barr virus encoded protein which has a 38% sequence similarity with bcl-2 over the carboxyl portion. Like bcl-2, BHRF1 has been shown to suppress programmed cell death from apoptosis. Previously BHRF1 has been detected in mitochondrial, microsomal, and nuclear compartments by cell fractionation analysis. In this study we have used the technique of immunoelectron microscopy t...
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rotavirus, a triple-layered non-enveloped member of the reoviridae family, obtained a transient membrane envelope when newly synthesized subviral particles bud into the endoplasmic reticulum (er). as rotavirus particles mature, they lose their transient membrane and obtain outer layer. it is mostly believed that only double layered particles bud into the er. the present study describes that the...
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It has been demonstrated that proteins covalently conjugated to folic acid may be taken up by cells via endocytosis after binding to a folate binding protein (FBP) in the cell membrane. The proteins taken up in this manner remain catalytically active and they may modify physiological processes occurring in the cytosol. Confocal fluorescence microscopy of KB cells incubated with FITC-bovine seru...
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The bcl-2 oncogene is expressed in lymphoid and myeloid cells as well as in neurons and several types of epithelial cells and inhibits programmed cell death (apoptosis). Deregulation by the t(14;18) translocation in lymphoid malignancies induces inappropriate cell survival and serves as one of the steps toward a fully malignant behavior. Using preand postembedding immunoelectron microscopy in n...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 1992
ISSN: 0022-1554,1551-5044
DOI: 10.1177/40.12.1453000